Measurement of rotavirus-neutralizing coproantibody in children by fluorescent focus reduction assay.

AUTOR(ES)

Coulson, B S

RESUMO

A fluorescent focus reduction assay suitable for the measurement of rotavirus-neutralizing antibodies in the feces of children was developed. Of 408 stools tested, 7% showed false-positive neutralization, and the number of rotavirus serotypes neutralized by a fecal extract was proportional to the levels of antirotaviral immunoglobulin A in the extract.

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