Microtiter Indirect Hemagglutination Procedure for Identification of Streptococcal M-Protein Antibodies

AUTOR(ES)

Zimmerman, Robert A.

RESUMO

A number of investigators have attempted to utilize the hemagglutination system for detection of streptococcal type-specific antibody in human sera. Cross-reactions have made the procedure unreliable without cumbersome and time-consuming manipulation of the test sera. A method is described in which a microtiter indirect hemagglutination technique, using sensitized sheep erythrocytes, is sensitive, specific, and reliable for titration of type-specific antibody after naturally acquired or induced streptococcal infection.

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