Minimal length of the lactose operator sequence for the specific recognition by the lactose repressor.
AUTOR(ES)
Bahl, C P
RESUMO
A number of specific duplex DNA sequences which correspond to varying lengths of the lactose operator region have been synthesized by a combination of chemical and enzymatic methods. Repressor binding studies on these synthetic duplex operator molecules show that all the nucleotides essential for full lactose operator-repressor interactions are included in a 17-nucleotide-long duplex DNA that constitutes the minimal recognition sequence for this DNA-protein interaction.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=430549Documentos Relacionados
- Chemical and enzymatic synthesis of lactose operator of Escherichia coli and its binding to lactose repressor.
- Functional recognition of fragmented operator sites by R17/MS2 coat protein, a translational repressor.
- Recognition of DNA structure by 434 repressor.
- Studies of gene control regions. III. Binding of synthetic and modified synthetic lac operator DNAs to lactose repressor.
- DNA twisting and the affinity of bacteriophage 434 operator for bacteriophage 434 repressor.
