Monitoring Retroviral RNA Dimerization In Vivo via Hammerhead Ribozyme Cleavage
AUTOR(ES)
Pal, Bijay K.
FONTE
American Society for Microbiology
RESUMO
We have used a strategy for colocalization of Psi (Ψ)-tethered ribozymes and targets to demonstrate that Ψ sequences are capable of specific interaction in the cytoplasm of both packaging and nonpackaging cells. These results indicate that current in vitro dimerization models may have in vivo counterparts. The methodology used may be applied to further genetic analyses on Ψ domain interactions in vivo.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=110209Documentos Relacionados
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