Morphogenesis of Newcastle Disease Virus in Chorioallantoic Membrane
AUTOR(ES)
Feller, Ursula
RESUMO
Chick embryo chorioallantoic membrane, infected with the Blacksburg strain of Newcastle disease virus, was examined with an electron microscope to investigate the sequence of viral-induced host cell alterations. These were evident mostly in the endodermal epithelial cells lining the allantoic sac and were divided arbitrarily into three stages. Stage 1 was characterized by commencement of cell hypertrophy and hyperplasia and presence of fewer cytoplasmic inclusion bodies normally found in the cells; in stage 2, juxtanuclear nucleocapsid-glycogen aggregates appeared, and there were increased numbers of microvilli; stage 3 was characterized by increased cytoplasmic density and evidence of viral assembly and release. The morphological features of viral assembly and the virion are also described.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=375934Documentos Relacionados
- SURVIVAL OF VARIOLA VIRUS IN CHORIOALLANTOIC MEMBRANE PREPARATIONS
- Evidence for Mixed Membrane Topology of the Newcastle Disease Virus Fusion Protein
- Translation and membrane insertion of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus.
- Mutational Analysis of Heptad Repeats in the Membrane-Proximal Region of Newcastle Disease Virus HN Protein
- Effect of in vitro adaptation of Marek's disease virus on pock induction on the chorioallantoic membrane of embryonated chicken eggs.
