Multiple Regulatory Mechanisms Act on the 5′ Untranslated Region of the S-Layer Gene from Thermus thermophilus HB8

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

The role of the 5′ untranslated region (5′UTR) of the S-layer gene from Thermus thermophilus was analyzed through the isolation of Δ5′UTR mutants. In these mutants the half-life of splA mRNA was strongly reduced and slpA transcription was no longer subjected to growth phase-dependent repression. Overproduction and detachment of the external envelopes of the mutants were observed in stationary phase.

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