Multiplicity of the Amino Acid Permeases in Saccharomyces cerevisiae IV. Evidence for a General Amino Acid Permease
AUTOR(ES)
Grenson, M.
RESUMO
Kinetic and genetic evidences are presented to show that, in addition to specific amino acid permeases, Saccharomyces cerevisiae has a general amino acid permease which catalyzes the transport of basic and neutral amino acids, but most probably not that of proline. The general amino acid permease appears to be constitutive, and its activity is inhibited when ammonium ions are added to the culture medium. A mutant which has lost the general amino acid permease activity was isolated. Its mutation, named gap (general amino acid permease), is not allelic to the aap (amino acid permease) mutation of Surdin et al., which has a quite different phenotype and cannot be considered as having selectively lost the general amino acid permease activity.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=248157Documentos Relacionados
- Positive selection of general amino acid permease mutants in Saccharomyces cerevisiae.
- Amino acids regulate the intracellular trafficking of the general amino acid permease of Saccharomyces cerevisiae
- Transcriptional and posttranslational regulation of the general amino acid permease of Saccharomyces cerevisiae.
- Ammonia regulation of amino acid permeases in Saccharomyces cerevisiae.
- Positive regulation in the general amino acid control of Saccharomyces cerevisiae.