Mutation of Escherichia coli capable of expressing gene(s) for beta-lactamase production of Citrobacter freundii.

AUTOR(ES)
RESUMO

A mutation in a chromosomal gene of Escherichia coli, designated reb, acted in trans to increase the expression of the cloned beta-lactamase gene of Citrobacter freundii. The reb gene was located around 99 min. Deletion mutants in the cloned gene(s) which had lost the regulatory region for induction were also constructed.

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