Mutational analysis of the carboxyl terminus of the Moloney murine leukemia virus integration protein.
AUTOR(ES)
Roth, M J
RESUMO
The integration protein (IN) is required for retrovirus DNA integration into the host DNA. The function of the C terminus of the Moloney murine leukemia virus IN protein was examined. The terminal 28 amino acids were found to be nonessential. A linker insertion at position 6025, within a 36-amino-acid insertion not found in any other retrovirus, also produced viable virus.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=240092Documentos Relacionados
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