New Delhi metallo-beta-lactamase-1-producing Acinetobacter spp. infection: report of a survivor

AUTOR(ES)

Schuelter-Trevisol, Fabiana, Schmitt, Graciane Jacinta, Araújo, Jane Martins de, Souza, Liliane Braga de, Nazário, Juliana Gomes, Januário, Raquel Landuchi, Mello, Rogério Sobroza de, Trevisol, Daisson José

FONTE

Rev. Soc. Bras. Med. Trop.

DATA DE PUBLICAÇÃO

2016-02

RESUMO

Abstract: New Delhi metallo-beta-lactamase-1 (NDM-1) is a bacterial enzyme that renders the bacteria resistant to a variety of beta-lactam antibiotics. A 20-year-old man was hospitalized several times for surgical treatment and complications caused by a right-sided vestibular schwannoma. Although the patient acquired several multidrug-resistant infections, this study focuses on the NDM-1-producing Acinetobacter spp. infection. As it was resistant to all antimicrobials tested, the medical team developed a 20-day regimen of 750mg/day metronidazole, 2,000,000IU/day polymyxin B, and 100mg/day tigecycline. The treatment was effective, and the patient recovered and was discharged from the hospital.

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