Novel Lysophospholipase A Secreted by Legionella pneumophila

AUTOR(ES)

Flieger, Antje

FONTE

American Society for Microbiology

RESUMO

We show that Legionella pneumophila possesses lysophospholipase A activity, which releases fatty acids from lysophosphatidylcholine. The NH2-terminal sequence of the enzyme contained FGDSLS, corresponding to a catalytic domain in a recently described group of lipolytic enzymes. Culture supernatants of a L. pneumophila pilD mutant lost the ability to cleave lysophosphatidylcholine.

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