Nucleotide sequence of the self-priming 3' terminus of the single-stranded DNA extracted from the parvovirus Kilham rat virus.
AUTOR(ES)
Salzman, L A
RESUMO
The parvovirus genome is a linear, single-stranded DNA molecule with double-stranded hairpin termini. The 3' terminus can serve in vitro as a self-primer for the synthesis of a double-stranded viral DNA intermediate. We have sequenced the nucleotides in the 3' terminus and propose a model for the secondary structure of the terminus and the in vitro origin of replication for the complementary viral DNA strand.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=353409Documentos Relacionados
- In vitro synthesis of double-stranded DNA from the Kilham rat virus single-stranded DNA genome.
- Restriction map of the single-stranded DNA genome of Kilham rat virus strains 171, a nondefective parvovirus.
- DNA of minute virus of mice: self-priming, nonpermuted, single-stranded genome with a 5'-terminal hairpin duplex.
- Linear, Single-Stranded Deoxyribonucleic Acid Isolated from Kilham Rat Virus
- In Vivo Conversion of the Single-Stranded DNA of the Kilham Rat Virus to a Double-Stranded Form