Ocular herpes simplex virus infections: reduced sensitivity to acyclovir in primary disease.
AUTOR(ES)
Charles, S. J.
RESUMO
Forty isolates of herpes simplex virus (HSV) obtained from ocular herpetic infections were assayed for their sensitivity to five antiviral agents. There were wide ranges of sensitivity to foscarnet, idoxuridine, and vidarabine, but the majority were sensitive to acyclovir and ganciclovir. Reduced sensitivity to acyclovir was seen in four isolates, all of which were from primary infections acquired in the community and without a previous history of treatment with antiviral drugs.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1042100Documentos Relacionados
- Immune response to herpes simplex virus infections: virus-specific antibodies in sera from patients with recurrent facial infections.
- Antiviral drug sensitivity in ocular herpes simplex virus infection.
- Acyclovir therapy of neonatal herpes simplex virus type 2 infections in rabbits.
- Effect of acyclovir treatment of primary genital herpes on the antibody response to herpes simplex virus.
- Oral acyclovir therapy of genital herpes simplex virus type 2 infections in guinea pigs.