Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements
AUTOR(ES)
Zhang, Zhaolei
FONTE
BioMed Central
RESUMO
Phylogenetic footprinting is an approach to finding functionally important sequences in the genome that relies on detecting their high degrees of conservation across different species. A new study shows how much it improves the prediction of gene-regulatory elements in the human genome.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=193683Documentos Relacionados
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- Keith R. Porter Lecture, 1996. Of mice and men: genetic disorders of the cytoskeleton.
