ON THE BIOSYNTHESIS AND STRUCTURE OF DOUBLE-STRANDED RNA IN VACCINIA VIRUS-INFECTED CELLS*

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RESUMO

The virus-specific, RNase-resistant RNA appearing in vaccinia virus-infected cells was directly shown to be an RNA duplex. After its melting and subsequent banding on Cs2SO4 or incubation with DNase, the RNA could be reannealed and then hybridized with vaccinia virus DNA.

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