Oxygenation of hydrocarbons by cytochrome P-450 model compounds: modification of reactivity by axial ligands.
AUTOR(ES)
Collman, J P
RESUMO
The rate of olefin oxygenation catalyzed by synthetic metalloporphyrins is examined, employing sodium hypochlorite as the oxygen atom source. The rate of epoxidation and the stability of the catalyst are shown to be dependent on the nature of the axial ligand employed. A rationale for this effect is presented and analogy is made to the role of the thiolate ligand in cytochrome P-450.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=390122Documentos Relacionados
- Epoxidation of olefins by cytochrome P-450 model compounds: mechanism of oxygen atom transfer.
- Position-specific oxygenation of benzo(a)pyrene by different forms of purified cytochrome P-450 from rabbit liver.
- Demethylation of Veratrole by Cytochrome P-450 in Streptomyces setonii
- Purification of a human liver cytochrome P-450 immunochemically related to several cytochromes P-450 purified from untreated rats.
- Degradation of Morpholine by an Environmental Mycobacterium Strain Involves a Cytochrome P-450