Paracoccidioides brasiliensis-stimulated human gamma/delta T cells support antibody production by B cells.
AUTOR(ES)
Munk, M E
RESUMO
Paracoccidioidomycosis patients show hyperactive humoral immune responses. Consequently, we investigated whether cytokines in supernatants from Paracoccidioides brasiliensis-stimulated gamma/delta T cells support B-cell activation. We detected proliferation of B cells and increased immunoglobulin M (IgM) and IgG production. Thus, gamma/delta T cells may participate in polyclonal B-cell activation during paracoccidioidomycosis.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=173198Documentos Relacionados
- Crosstalk between alpha/beta T cells and gamma/delta T cells in vivo: activation of alpha/beta T-cell responses after gamma/delta T-cell modulation with the monoclonal antibody GL3.
- Pregnancy and gamma/delta T cells: Taking on the hard questions
- Listeria monocytogenes-induced gamma interferon secretion by intestinal intraepithelial gamma/delta T lymphocytes.
- Gamma/delta cells in tissue from patients with sarcoidosis.
- Clonal expansions of activated gamma/delta T cells in recent-onset multiple sclerosis.