Partial Inhibition of Polysomal Ribosomes of Escherichia coli by Streptomycin
AUTOR(ES)
Wallace, Brian J.
RESUMO
With purified initiation-free polysomes of E. coli, whether endogenous or formed in vitro on phage R17 RNA, streptomycin causes partial inhibition of chain elongation. The degree of inhibition is constant over a broad range of streptomycin concentration and decreases markedly with increasing Mg++ concentration. Hence, streptomycin evidently complexes readily with polysomal ribosomes, causing a partial block in chain elongation.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=433465Documentos Relacionados
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