Partial Reassociation Between the Deoxyribonucleic Acids of Neisseria lactamicus and Neisseria meningitidis1

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RESUMO

The similarity in polynucleotide sequence of seven strains of Neisseria lactamicus to N. meningitidis and to each other was investigated. The per cent reassociation between single-stranded N. lactamicus deoxyribonucleic acid (DNA), immobilized on membrane filters, with labeled single-stranded DNA fragments derived from strain SD-6 (group C) of N. meningitidis varied from 75 to 56. With strain ATCC 23972 of N. lactamicus furnishing the labeled DNA fragments, reassociation was 72% with N. meningitidis, 31% with N. subflava, and 98 to 72% with the other strains of N. lactamicus. It is concluded that on the basis of DNA reassociation N. lactamicus can be distinguished from N. meningitidis and N. subflava, but constitutes a relatively heterogeneous species.

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