PCR amplification of variable sequence upstream of katG gene to subdivide strains of Mycobacterium tuberculosis complex.
AUTOR(ES)
Goyal, M
RESUMO
PCR amplification of a species-specific 2-kb KpnI fragment of variable size located 10 kb upstream of the katG gene was used to subdivide 130 clinical isolates of Mycobacterium tuberculosis. Seven subtypes were identified, and their frequencies were distributed normally with respect to the size of the amplified product.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=264232Documentos Relacionados
- Molecular analysis of katG gene mutations in strains of Mycobacterium tuberculosis complex from Africa.
- Presence of katG gene in resistant Mycobacterium tuberculosis.
- katG mutations in isoniazid-resistant strains of Mycobacterium tuberculosis are not infrequent.
- Detection of Isoniazid-Resistant Mycobacterium tuberculosis Strains by a Multiplex Allele-Specific PCR Assay Targeting katG Codon 315 Variation
- Nucleotide sequence of the Mycobacterium leprae katG region.