Penetration of sulbactam and ampicillin into cerebrospinal fluid of infants and young children with meningitis.
AUTOR(ES)
Foulds, G
RESUMO
Infusions of 50 mg of sulbactam per kg per day and 400 mg of ampicillin per kg per day in divided doses to infants and children with bacterial meningitis produced levels in cerebrospinal fluid approximately one-third those in serum. Concentrations in cerebrospinal fluid of 5.5 micrograms of sulbactam per ml and 16.0 micrograms of ampicillin per ml declined within a few days of therapy to 1.9 microgram of sulbactam per ml and 5.2 micrograms of ampicillin per ml.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=175024Documentos Relacionados
- Penetration of cefoxitin into cerebrospinal fluid of infants and children with bacterial meningitis.
- Penetration of pefloxacin into cerebrospinal fluid of patients with meningitis.
- Moxalactam penetration into cerebrospinal fluid in patients with bacterial meningitis.
- Cefoxitin penetration into cerebrospinal fluid in patients with purulent meningitis.
- Cefotaxime diffusion into cerebrospinal fluid of children with meningitis.