Penicillin-Binding Proteins 1a and 1b Form Independent Dimers in Escherichia coli

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

We report here that PBP1a can dimerize but does not interact with PBP1b to form PBP1a/PBP1b heterodimers in Escherichia coli. These findings support the idea of a relevant involvement of dimerization of both PBP1a and PBP1b during murein synthesis and suggest the existence of different peptidoglycan synthesis complexes.

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