Periodic loss of reactivity of a myeloma tumor with cytotoxic thymus-derived lymphocytes.
AUTOR(ES)
Russell, J H
RESUMO
During each transplantation passage of a line of mouse myeloma tumor MOPC-315 through syngeneic (BALB/c) hosts, the tumor cells lose reactivity with cytotoxic thymus-derived lymphocytes directed against products of the BALB/c major histocompatibility complex (H-2d) and regain reactivity on transfer to fresh hosts. In contrast to this cyclical change, the tumor cells remain uniformly reactive with anti-H-2d alloantisera throughout the transplantation cycle.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=411265Documentos Relacionados
- Recognition of immunoglobulin idiotypes by thymus-derived lymphocytes.
- Release of colony-stimulating activity from thymus-derived lymphocytes.
- Heterogeneity of the cytotoxic response of thymus-derived lymphocytes after immunization with influenza viruses.
- Suppressor thymus-derived lymphocytes in fungal infection.
- Regulation of magnitude of antibody response to bacterial polysaccharide antigens by thymus-derived lymphocytes.
