Persistence of Burkholderia multivorans within the Pulmonary Macrophage in the Murine Lung
AUTOR(ES)
Chu, Karen K.
FONTE
American Society for Microbiology
RESUMO
Differences in infection kinetics and host response between Burkholderia multivorans and Burkholderia cenocepacia were demonstrated in a pulmonary infection model in BALB/c mice. B. multivorans persisted in the lung, while B. cenocepacia was cleared. Indirect immunofluorescence and electron microscopy of B. multivorans-infected lungs localized bacteria to macrophages. Clearance of B. cenocepacia was associated with greater interleukin-1β and neutrophil responses than the responses induced by B. multivorans.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=517555Documentos Relacionados
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