Pharmacological observations in patients with nodoventricular pathways.

AUTOR(ES)

Strasberg, B

RESUMO

Three patients with accessory nodoventricular pathways and re-entry tachycardia are reported. In all three patients the accessory nodoventricular pathway formed the anterograde limb of the re-entry circuit while the His-Purkinje-atrioventricular node axis formed the retrograde limb of the tachycardia in two of the patients and a concealed accessory pathway formed the retrograde limb in the remaining patient. All three patients also manifested dual anterograde atrioventricular nodal pathways with conduction through the accessory nodoventricular pathways being associated with the atrioventricular nodal fast pathway. Type I antiarrhythmic drugs, especially disopyramide and quinidine, were effective for the treatment of the re-entry tachycardia because of their depressive action on the nodoventricular pathway. Beta blockers were also effective because of their action on the atrioventricular nodal portion of the re-entry circuit in one patient and most probably due to atypical (atrioventricular nodal like) properties of a retrogradely conducting accessory pathway in a second patient.

Documentos Relacionados

• Inhibition of exercise-induced asthma by different pharmacological pathways.
• Outflow pathways.
• Patterns of atrial activation during right ventricular pacing in patients with concealed left-sided Kent pathways.
• Stereospecificity in meta-fission catabolic pathways.
• Hypertrophic cardiomyopathy: a case study in converging pathways.