Physical Properties of Lactic Dehydrogenase-Elevating Virus and Its Ribonucleic Acid

AUTOR(ES)

Darnell, Margo B.

RESUMO

Infectious lactic dehydrogenase-elevating virus propagated in primary cultures of mouse peritoneal macrophages in the presence of 3H-uridine and isolated by isopycnic centrifugation was found to have a density of 1.12 g/cm3. Ribonucleic acid extracted from the virus by treatment with sodium dodecyl sulfate was single stranded with a sedimentation coefficient of approximately 48S.

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