PLC/PRF/5 (Alexander) hepatoma cell line: further characterization and studies of infectivity.
AUTOR(ES)
Daemer, R J
RESUMO
The Alexander hepatoma cell line, PLC/PRF/5, was studied for evidence of hepatitis B virus markers and alpha-fetoprotein. Only hepatitis B surface antigen and alpha-fetoprotein were detected. Induction experiments with 5-iodo-2'-deoxyuridine and inoculation of chimpanzees with whole cells or tissue culture fluid did not reveal evidence of synthesis of additional hepatitis B virus markers or of production of infectious virus.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=551353Documentos Relacionados
- The genetic organization of integrated hepatitis B virus DNA in the human hepatoma cell line PLC/PRF/5
- Characterization of integrated hepatitis B viral DNA cloned from a human hepatoma and the hepatoma-derived cell line PLC/PRF/5.
- The genetic organization of integrated hepatitis B virus DNA in the human hepatoma cell line PLC/PRF/5.
- Inhibitory effects of atropine, protamine, and their combination on hepatitis A virus replication in PLC/PRF/5 cells.
- Integrated hepatitis B virus DNA sequences specifying the major viral core polypeptide are methylated in PLC/PRF/5 cells.