Pneumolysin Potentiates Production of Prostaglandin E2 and Leukotriene B4 by Human Neutrophils
AUTOR(ES)
Cockeran, Riana
FONTE
American Society for Microbiology
RESUMO
Exposure to pneumolysin (8.37 and 41.75 ng/ml) caused a calcium-dependent increase in the generation of prostaglandin E2 and leukotriene B4 by both resting and chemoattractant-activated human neutrophils in vitro. These interactions of pneumolysin with neutrophils may result in dysregulation of inflammatory responses during pneumococcal infection.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=98318Documentos Relacionados
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