Polyamine Synthesis and Accumulation in Escherichia coli Infected with Bacteriophage R17
AUTOR(ES)
Fukuma, Isamu
RESUMO
We have studied the biosynthesis of polyamines during the multiplication of the RNA bacteriophage R17. R17-sensitive strains of Escherichia coli were derived from the stringent CP78 and the relaxed mutant derivative CP79. The cells were infected with R17 in the presence or absence of arginine, a required amino acid, and both the RNA and polyamine contents of the bacteria were determined before and after the infection. The uninfected CP79 rel derivative accumulated RNA and spermidine in the absence of arginine, unlike the stringent organism that accumulated neither under these conditions. After R17 infection, the stringent strain accumulated RNA and spermidine in the presence or absence of arginine. The data indicate a close correlation between the synthesis of RNA and spermidine, suggesting a significant role for this polyamine in the multiplication of phage R17.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=356766Documentos Relacionados
- Synthesis of Soluble Ribonucleates in Escherichia coli Infected with Bacteriophage R17
- Ultrastructure of Escherichia coli Cells Infected with Bacteriophage R17
- High Resolution Autoradiography of Escherichia coli Cells Infected with Bacteriophage R17
- Elimination of the Early Inhibition of Protein Synthesis in Escherichia coli C3000 Infected with Purified R17 Bacteriophage
- Alterations in the Distribution of Labeled Ribonucleic Acid in Polyribosomes from Escherichia coli Infected with Bacteriophage R17
