Polyploids and Sex Determination in CAENORHABDITIS ELEGANS
AUTOR(ES)
Madl, James E.
RESUMO
Tetraploid stocks of Caenorhabditis elegans var. Bristol carrying autosomal and X-linked markers have been produced. Tetraploid hermaphrodites fall into two categories: those that give about 1% male self-progeny and those that give 25 to 40% male self-progeny. The former are basically 4A;4X—four sets of autosomes and four sex chromosomes—and the latter are 4A;3X. Males are 4A;2X. (Diploid hermaphrodites are 2A;2X; males are 2A;1X.) Triploids were produced by crossing tetraploid hermaphrodites and diploid males. Triploids of composition 3A;3X are hermaphrodites; 3A;2X animals are fertile males. Different X-chromosome duplications were added to a 3A;2X chromosome constitution to increase the X-to-autosome ratio. Based on the resulting sexual phenotypes, we conclude that there exists on the C. elegans X chromosome at least three (and perhaps many more) dose-sensitive sites that act cumulatively in determining sex.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1214087Documentos Relacionados
- Sex Determination in Polyploids of Caenorhabditis Elegans
- More Sex-Determination Mutants of CAENORHABDITIS ELEGANS
- RNA and sex determination in Caenorhabditis elegans: Post-transcriptional regulation of the sex-determining tra-2 and fem-3 mRNAs in the Caenorhabditis elegans hermaphrodite
- An Autosomal Gene That Affects X Chromosome Expression and Sex Determination in CAENORHABDITIS ELEGANS
- The Caenorhabditis Elegans Gene Sdc-2 Controls Sex Determination and Dosage Compensation in Xx Animals
