Polyprotein Processing Protease of African Swine Fever Virus: Purification and Biochemical Characterization

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

The purified recombinant African swine fever virus polyprotein processing protease cleaves the two GG-X sites in polyprotein pp62 with the same efficiency. Cleavage at the site that is first recognized in vivo is not a requisite for cleavage at the second site, suggesting the existence of mechanisms that control the ordered processing of the polyprotein during infection.

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