Porcine Endogenous Retrovirus Transmission Characteristics of an Inbred Herd of Miniature Swine

AUTOR(ES)

Oldmixon, Beth A.

FONTE

American Society for Microbiology

RESUMO

Here we report the identification of inbred miniature swine that failed to produce human-tropic replication-competent porcine endogenous retroviruses (HTRC PERVs), using in vitro coculture assays. When HTRC PERVs were isolated from transmitting animals, all were recombinant viruses, with the receptor-binding domain of PERV-A combining with PERV-C-related sequences.

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