Porphyromonas gingivalis RgpA and Kgp Proteinases and Adhesins Are C Terminally Processed by the Carboxypeptidase CPG70

AUTOR(ES)

Veith, Paul D.

FONTE

American Society for Microbiology

RESUMO

Porphyromonas gingivalis is a bacterial pathogen that produces the polyproteins RgpA and Kgp, which are proteolytically processed into proteinases and adhesins. We have demonstrated that the RgpA and Kgp proteinases and adhesins are C terminally processed by carboxypeptidase CPG70 by sequencing C-terminal peptides from both the wild type and an isogenic CPG70 mutant, using ion trap mass spectrometry.

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