Potentiation of Isoniazid Activity against Mycobacterium tuberculosis by Melatonin
AUTOR(ES)
Wiid, Ian
FONTE
American Society for Microbiology
RESUMO
The limited number of effective antituberculosis drugs available necessitates optimizing current treatments. We show that melatonin, which is synthesized in the pineal gland, can cause at least a threefold increase in the efficacy of isoniazid. This suggests that tuberculosis chemotherapy can be improved by innate molecules such as melatonin.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=89241Documentos Relacionados
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