Preferred analysis methods for Affymetrix GeneChips revealed by a wholly defined control dataset

AUTOR(ES)

Choe, Sung E

FONTE

BioMed Central

RESUMO

A 'spike-in' experiment for Affymetrix GeneChips is described that provides a defined dataset of 3,860 RNA species. A 'best route' combination of analysis methods is presented which allows detection of approximately 70% of true positives before reaching a 10% false discovery rate.

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