Prenatal diagnosis of a de novo Y/22 translocation.
AUTOR(ES)
Verjaal, M
RESUMO
Prenatal chromosomal analysis was performed at 17 weeks' gestation because of the previous birth of a girl with trisomy 13. A seemingly balanced de novo Y/22 translocation was diagnosed. Translocations involving the Y chromosome are rare and no similar translocation, detected pre- or postnatally, could be found in published reports. The counselling problems are discussed. The pregnancy ended at term with the birth of a phenotypically normal boy. After birth, the prenatal diagnosis was confirmed and the H-Y antigen expression was determined.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1013765Documentos Relacionados
- "Pure" partial trisomy 4q25-qter owing to a de novo 4;22 translocation.
- Prenatal diagnosis of a de novo non-fluorescent Y chromosome.
- Isolation of BAC clones spanning the Xq22.3 translocation breakpoint in a lissencephaly patient with a de novo X;2 translocation.
- Prenatal lethality in a transgenic mouse line is the result of a chromosomal translocation.
- Features of Turner's and DiGeorge's syndromes with X;22 translocation.