Procaryotic genomic DNA inhibits mammalian cell transformation.
AUTOR(ES)
Yoder, J I
RESUMO
Ltk- mouse cells were transformed to thymidine kinase prototrophy in the presence of carrier DNAs isolated from different organisms. Procaryotic genomic and phage DNA was consistently less effective as a carrier than was eucaryotic DNA. Mixing experiments indicate that DNA of procaryotic origin inhibits mammalian cell transformation.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=368618Documentos Relacionados
- Characterization of the genomic RNA from a Rous sarcoma virus mutant temperature sensitive for cell transformation.
- DMSO-enhanced whole cell yeast transformation.
- Herpesvirus saimiri DNA in a lymphoid cell line established by in vitro transformation.
- Cell cycle control of polyomavirus-induced transformation.
- Sequence-specific DNA uptake in Haemophilus transformation.
