Prostaglandin E2 Mediates Cough via the EP3 Receptor: Implications for Future Disease Therapy
AUTOR(ES)
Maher, Sarah A.
FONTE
American Thoracic Society
RESUMO
Rationale: A significant population of patients with severe asthma and chronic obstructive pulmonary disease is less responsive to β2-adrenoceptor agonists and corticosteroids, and there are possible safety issues concerning long-term use of these drugs. Inhaled prostaglandin E2 (PGE2) is antiinflammatory and a bronchodilator in patients with asthma, but it also causes cough.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2778154Documentos Relacionados
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