Protective effect of monoclonal antibodies on lethal mouse hepatitis virus infection in mice.
AUTOR(ES)
Nakanaga, K
RESUMO
Neutralizing and nonneutralizing monoclonal antibodies to the peplomer glycoprotein and nucleocapsid protein of a mouse hepatitis virus (MHV), MHV-NuU, protected mice against lethal MHV-2 challenge. Histopathologically, livers of mice receiving protective antibodies showed some focal necrotic lesions with remarkable cellular infiltration instead of fulminant hepatitis caused by MHV-2.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=253053Documentos Relacionados
- A protective monoclonal anti-idiotypic vaccine to lethal Semliki Forest virus infection in BALB/c mice.
- Protective effect of Lactobacillus casei on Pseudomonas aeruginosa infection in mice.
- New strain of mouse hepatitis virus as the cause of lethal enteritis in infant mice.
- Urease-specific monoclonal antibodies prevent Helicobacter felis infection in mice.
- Protective effect of human granulocyte colony-stimulating factor on microbial infection in neutropenic mice.