Quality Control in Nucleic Acid Amplification Methods: Use of Elementary Probability Theory
AUTOR(ES)
Shapiro, Daniel S.
FONTE
American Society for Microbiology
RESUMO
Since it is not possible to state with certainty that contamination has occurred during a nucleic acid amplification assay in the absence of a positive result for a negative control, methods of elementary probability theory are used to illustrate how to identify those runs in which the possibility of contamination should be considered. The use of binomial and Poisson distributions and an analysis of clusters are presented with illustrative examples to demonstrate their use.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=84582Documentos Relacionados
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