Rapid Detection of a Molecular Marker for Chloroquine-Resistant Falciparum Malaria
AUTOR(ES)
Durand, Rémy
FONTE
American Society for Microbiology
RESUMO
A PCR-based technique using molecular beacons was developed to detect the chloroquine resistance-associated pfcrt K76T point mutation in Plasmodium falciparum. One hundred thirty African clinical isolates were tested by the new method in comparison with the PCR-restriction fragment length polymorphism method. This rapid and inexpensive genomic assay could expand the possibilities for monitoring chloroquine resistance.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=127343Documentos Relacionados
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