recD sbcB sbcD Mutants Are Deficient in Recombinational Repair of UV Lesions by RecBC

AUTOR(ES)

Seigneur, Marie

FONTE

American Society for Microbiology

RESUMO

In recD sbcB sbcD mutants, repair of UV-irradiated DNA is strongly RecF dependent, indicating that RecBC is inactive. This finding suggests that exonuclease V, exonuclease I (SbcB), and the SbcCD nuclease play a redundant role in vivo, which is essential for the recombination activity of the RecBC complex during UV repair.

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