Recovery of norfloxacin in feces after administration of a single oral dose to human volunteers.
AUTOR(ES)
Cofsky, R D
RESUMO
Twelve healthy volunteers received single 400-mg oral doses of norfloxacin. During the ensuing 48 h, from 8.3 to 53.3% (mean, 28%) of this dose was recovered in the feces. Peak drug concentrations in fecal specimens ranged from 207 to 2,716 micrograms/g.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=179930Documentos Relacionados
- Fosfomycin kinetics after intravenous and oral administration to human volunteers.
- Bioequivalence of oral and intravenous ofloxacin after multiple-dose administration to healthy male volunteers.
- Concentration of norfloxacin in human gallbladder tissue and bile after single-dose oral administration.
- Inter- and intrasubject variabilities in the pharmacokinetics of rufloxacin after single oral administration to healthy volunteers.
- BRL-36650: in vitro studies and assessment of serum bactericidal activity after single-dose administration in volunteers.