Refinement of a chimpanzee pericentric inversion breakpoint to a segmental duplication cluster

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BioMed Central

RESUMO

A comparative fluorescence in situ hybridization approach, using probes selected from a combination of physical mapping, genomic sequence, and segmental duplication analyses has been employed to narrow the breakpoint interval of a pericentric inversion in chimpanzee involving the orthologous human 15q11-q13 region.

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