Regulation of Cholesterol Metabolism in the Dog: II. EFFECTS OF COMPLETE BILE DIVERSION AND OF CHOLESTEROL FEEDING ON POOL SIZES OF TISSUE CHOLESTEROL MEASURED AT AUTOPSY

AUTOR(ES)

Pertsemlidis, Demetrius

RESUMO

In six adult pedigreed dogs the effects of high-cholesterol diets or bile diversion on the sizes of body cholesterol pools were studied at autopsy. Total body cholesterol was determined by measuring the cholesterol content of discrete organs and of the eviscerated carcass: neither cholesterol feeding nor bile diversion had altered total body cholesterol or the cholesterol content of individual organs and tissues. These results validated the conclusion based on sterol balance data obtained during life, that high-cholesterol feeding did not lead to substantial expansion of tissue cholesterol pools.

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