Regulation of protein synthesis at the translational level in neuroblastoma cells.
AUTOR(ES)
Zucco, F
RESUMO
Protein synthesis in reuroblastoma cells has been studied in a cell-free system. The activity of lysates from cells grown insuspension and monolayer has been compared. A higher level of activity has been found in monolayer cells. The activity of some components of the lysate that are involved in protein synthesis has been analyzed.The data suggest that the controlling step of protein synthesis in this system might be in the initiation process. The correlation between activation of protein synthesis and neurite outgrowth in monolayer cultures is discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=432743Documentos Relacionados
- Presence of free cyclic AMP receptor protein and regulation of its level by cyclic AMP in neuroblastoma-glioma hybrid cells.
- Hemoglobin F synthesis in vitro: evidence for control at the level of primitive erythroid stem cells.
- Repression of enzyme synthesis at the translational level and its hormonal control.
- Regulation of acetylcholine release from neuroblastoma x glioma hybrid cells.
- Hormonal regulation of protein synthesis, secretion, and phosphorylation in cultured rat Sertoli cells.
