Repair and subsequent fragmentation of deoxyribonucleic acid in ultraviolet-irradiated Bacillus subtilis recA.
AUTOR(ES)
Hadden, C T
RESUMO
Cells of Bacillus subtilis recA1 are sensitive to irradiation with ultraviolet light. Evidence is presented here that these cells are not defective in ultraviolet light-induced incision of deoxyribonucleic acid (DNA) or repair DNA synthesis. Ligation of DNA at repair sites appears to occur, but the DNA is subsequently fragmented, apparently at sites of previous repair synthesis. It is hypothesized that the defect in DNA repair leads to host-specific restriction at repaired sites because of a defect in either the structure of the repaired region or specificity of the restriction/modification system.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=235588Documentos Relacionados
- Postreplication repair of ultraviolet-irradiated transforming deoxyribonucleic acid in Bacillus subtilis.
- Repair of Ultraviolet-Irradiated Transforming Deoxyribonucleic Acid in Haemophilus influenzae
- Fate of Thymine-containing Dimers in the Deoxyribonucleic Acid of Ultraviolet-irradiated Bacillus subtilis
- Integration and Repair of Ultraviolet-Irradiated Transforming Deoxyribonucleic Acid in Haemophilus influenzae
- In Vitro Excision-Repair of Ultraviolet-Irradiated Transforming DNA from Bacillus subtilis