Repeating modular structure of the fibronectin gene: relationship to protein structure and subunit variation.
AUTOR(ES)
Odermatt, E
RESUMO
Analysis of the exon-intron structure of the rat fibronectin gene shows that exons correspond precisely with repeating structural units in the protein and that alternative use of some exons produces fibronectin subunits that differ by the presence or absence of certain structural modules. Secondary structure predictions suggest that the repeating structure of the protein is further subdivided into smaller structural units and that these also correspond with exons in the gene.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=391251Documentos Relacionados
- Small repeating units within the Ureaplasma urealyticum MB antigen gene encode serovar specificity and are associated with antigen size variation.
- Structure of the CD59-encoding gene: further evidence of a relationship to murine lymphocyte antigen Ly-6 protein.
- Parathion hydrolase specified by the Flavobacterium opd gene: relationship between the gene and protein.
- Mapping evolution with ribosome structure: intralineage constancy and interlineage variation.
- Structure of the chicken link protein gene: exons correlate with the protein domains.