Replication Process of the Parvovirus H-1 I. Kinetics in a Parasynchronous Cell System
AUTOR(ES)
Rhode, Solon L.
RESUMO
Parasynchronous cultures of hamster embryo cells were used to study some of the events in the replication process of the parvovirus H-1. Synthesis of viral DNA, viral hemagglutinating antigen, and infectious virus were examined. It was found that initiation of DNA synthesis, on which subsequent viral hemagglutinin synthesis was dependent, occurred at a specific time in late S-phase. Production of H-1 viral protein was shown to be sensitive to inhibition by α-amanitin. The implications of these findings are discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=355192Documentos Relacionados
- Replication Process of the Parvovirus H-1 III. Factors Affecting H-1 RF DNA Synthesis
- Replication Process of the Parvovirus H-1 II. Isolation and Characterization of H-1 Replicative Form DNA
- Replication process of the parvovirus H-1 V. Isolation and characterization of temperature-sensitive H-1 mutants.
- Replication process of the parvovirus H-1. VI. Characterization of a replication terminus of H-1 replicative-form DNA.
- Replication process of the parvovirus H-1. IX. Physical mapping studies of the H-1 genome.
