Replication termination for staphylococcal plasmids: plasmids pT181 and pC221 cross-react in the termination process.
AUTOR(ES)
Iordanescu, S
RESUMO
We present data which indicate that (i) the origin of replication of plasmids pT181 and pC221 can also function as termination signals; (ii) termination of replication occurs when a round of replication initiated either by RepC at the pT181 origin or by RepD at the pC221 origin reaches either of these origins, proving that the two plasmids cross-react for termination of replication; and (iii) the replication initiated at the origin of another staphylococcal plasmid, pE194, does not terminate at the origin of pT181 or pC221, indicating the existence of a specific relationship between the initiation and termination of a replication event.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=211311Documentos Relacionados
- Plasmids of the pT181 family show replication-specific initiator protein modification.
- Intermediates in plasmid pT181 DNA replication.
- Control of pT181 replication I. The pT181 copy control function acts by inhibiting the synthesis of a replication protein.
- Control of pT181 replication II. Mutational analysis.
- Mobilization of the relaxable Staphylococcus aureus plasmid pC221 by the conjugative plasmid pGO1 involves three pC221 loci.